Blue Light: Interview with Prof. Giuseppe Querques, Italy
Prof. Giuseppe Querques
Publication: Points de Vue, the International Review of Ophthalmic Optics

Key Highlights:

  • Age-related macular degeneration is a premature aging of the retina.
  • Several factors come into play in this multifactorial disease, including those with an inflammatory effect, as well as the genetic background.
  • Blue-violet light is mainly responsible for the process of apoptosis as it causes a photochemical phenomenon that leads to the overloading of retinal pigment epithelium cells with an extremely toxic component, named lipofuscin.
  • We can try to reduce the apoptotic process by adopting a combined approach.
  • Large steps have been taken to demonstrate the negative effect of blue-violet light on retinal cells in the macula and thus on the retinal pigment epithelium and photoreceptors.
  • Studies have evidenced that light wavelengths from 415 to 455 nanometers are particularly harmful.

Professor Giuseppe Querques  is Associate Professor and Head of Medical Retina & Imaging Unit at University Vita-Salute, Milan, Italy.

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